The Bioassay laboratory (BL) is intended to serve as a national resource platform for the clinical development of vaccines and biologicals and aims to provide clinical assay services for vaccine-preventable pathogens as per the regulatory standards. The laboratory has currently established molecular and serological assays for Dengue and Chikungunya and is awaiting accreditation from the National Accreditation Board for Testing and Calibration Laboratories (NABL) as per the ISO-17025:2017 standard.
To be the best laboratory in India for providing accredited assay services for vaccine development
To continuously strive to provide clinical assay services that are of highest quality and standard to industry and academia thereby positively contributing to public health.
With an area of around 2000 sq. ft., the laboratory has been set up as per the guidelines of NABL. Eight separate rooms have been created to maintain unidirectional workflow and segregate the activities such as Flow cytometry, Serology, Reagent preparation, Nucleic acid isolation, Template addition, PCR and post-PCR rooms and Animal cell culture for virus cultivation. All equipment has been calibrated and validated as per the NABL requirements.
The Bioassay Laboratory at THSTI can be used by any organization requiring expertise in:
Immunogenicity studies
Cell-Based Assays
Sero-epidemiology
Etiology
Bioassay laboratory is one of the four institutional support facilities of THSTI under the TRP funded by DBT. The TRP team under this project is actively working on cell culture-based assays and ELISA for Dengue, Chikungunya and SARS-CoV-2.
Bioassay lab at THSTI has been established with support from DBT's IndCEPI grant. Recently, BL was selected as one of the seven labs in the world to provide validated assays for COVID-19 vaccine development. The other labs in the network are Nexelis, Canada; PHE, UK; ICDDR, Bangladesh; Q2 Solutions, USA; Viroclinics, Netherlands; and Vismederi, Italy.
Since 2018, the core technical team has been working towards the establishment of Bioassay laboratory at THSTI
The Quality team ensures the compliance to Quality Policy and objectives at Bioassay laboratory, THSTI
