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Patents and Licensing

THSTI TECHNOLOGIES AND LICENSING OPPORTUNITY

THSTI seeks industry partners with demonstrated technical capabilities and business management resources to commercialize Laboratory inventions. Our innovations, combined with your business acumen, can work together to give your company a competitive advantage in the marketplace and propel the Indian economy forward. All licensing activities are conducted under policies relating to the strict nondisclosure of company proprietary information.

S. No. Patent Application No. Title Inventor(s) Owner(s) IP status *Last Date to apply Licensing Status
1 PCT/IN2019/050827 A novel aptamer, aptamer based electrochemical biosensor for the rapid diagnosis of tuberculous meningitis and methods of detecting tuberculous meningitis Tarun Kumar Sharma, Prof. Jaya Tyagi, Ritu Das, Abhijeet Dhiman THSTI, AIIMS, M/s Aptabharat Innovations PCT application Open
2 201911046890 Integrative Expression Vector Bhabatosh Das, Archana Pant, Jyoti Verma, Shailendra Vyas THSTI, Bioheaven 360 Provisional Indian patent application Open
3 201911036350 Novel DNA aptamers against venom of Bungarus caeruleus, method of its chemical synthesis and uses thereof Dr. Tarun Kumar Sharma, Ms. Anjali Anand THSTI Provisional Indian Patent application Open
4 201911036660 Engineered HIV-1 Envelope Immunogen Dr. Jayanta Bhattacharya, Dr. Rajesh Kumar, Mr. Vivek Kumar, Dr. Suprit Despande, Dr. Murugavel Kailapuri Gangatharan THSTI, IAVI, YRG Care Provisional Indian Patent Application Open
5 PCT/IN2019/050718 A pharmaceutical composition for the treatment of TH17 cells mediated autoimmune diseases Dr. Amit Awasthi, Dr. Amit Kumar Pandey, Dr. Shailendra Asthana, Dr. Zaigham Abbas Rizvi, Charu Suri, Srikant Sadhu, Suyasha Roy THSTI PCT application Open
6 201911027455 Aptamers against phospholipase A2 in snake venom and uses thereof. Dr. Tarun Kumar Sharma, Ms. Anjali Anand, Dr. Robin Doley THSTI, Tezpur University Provisional patent application Open
7 201911027069 A H1N1 Influenza virus M2e ectodomain protein obtained from an arrangement of M2e ectodomain polypeptides and uses thereof. Dr. Sweety Samal, Dr. Rajesh Kumar, Dr. Tripti Shrivastava, Naresh Kumar, Manish Bansal THSTI Provisional patent application Open
8 201911025444 A recombinant mycobacterium strain with constitutively activated toxin VapC12 and uses thereof. Dr. Amit Kumar Pandey, Mr. Manitosh Pandey, Ms. Sakshi Talwar THSTI Indian provisional Open
9 201911013070 Zinc Chelators as inhibitor of Dengue Virus Replication and Uses thereof Dr. Guruprasad Medigeshi THSTI Indian Provisional Open
10 201911013062 Mutant HEV pORF2 based antigens and uses thereof Dr. Milan Surjit, Jyoti Gupta THSTI Indian Provisional Open
11 201911015320 Method of preparing nutraceutical and pharmaceutical products based on musa balbisiana and uses thereof Dr. Sima Kumari, Dr. Sanjay Banerjee, Dr. Rajlakshmi Devi, Dr. Dinesh Mahajan, Dr. Yashwant Kumar THSTI, IASST Guwahati Indian Provisional Open
12 US10207993 Novel Compounds as anti-Tubercular Agents Varshenya Singh, Dr. KV Subba Rao, Dr. Dinesh Mahajan, Dr. Sundeep Duggar THSTI, Sphaera Pharma Granted US patent NA
13 US10100012 Novel Compounds as anti-Tubercular Agents Varshenya Singh, Dr. KV Subba Rao, Dr. Dinesh Mahajan, Dr. Sundeep Duggar THSTI, Sphaera Pharma Granted US patent NA
14 16/346,625 Method of Converting Carbon Dioxide into Carbonyl Compounds Dr. Dinesh Mahajan, Varun Kumar, Anil Rana THSTI US national phase Open
15 201917016835 Method of Converting Carbon Dioxide into Carbonyl Compounds Dr. Dinesh Mahajan, Varun Kumar, Anil Rana THSTI Indian, national phase Open
16 15/674033 Novel Compounds as anti-Tubercular Agents Varshenya Singh, Dr. KV Subba Rao, Dr. Dinesh Mahajan, Dr. Sundeep Duggar THSTI, Sphaera Pharma US Divisional NA
17 PCT/IN2018/050475 A cyclic peptide and pharmaceutical composition coprising the same for the inhibition of HEV proliferation Dr. Milan Surjit, Saumya Anang THSTI PCT application Open
18 PCT/IN2018/050581 Aptamer against M.tb MPT51 and uses thereof Dr. Jaya S. Tyagi, Dr. Tarun Kumar Sharma, Dr. Abhijeet Dhiman, Dr. Ritu Das THSTI, AIIMS, Aptabharat Innovation Private Limited PCT application NA
19 PCT/IN2018/050648 Method of Converting Carbon Dioxide into Carbonyl Compounds Dr. Dinesh Mahajan, Varun Kumar, Anil Rana THSTI PCT application Open
20 PCT/IN2018/050575 A pharmaceutical composition for the treatment of IL9 mediated autoimmune inflammatory diseases and uses thereof Dr. Amit Awasthi, Suyasha Roy THSTI PCT application Open
21 201811042593 Aptamer based electrochemical biosensor for the rapid diagnosis of Tuberculosis Meningitis Dr. Tarun Sharma, Dr. Jaya Sivaswami Tyagi, Dr. Abhijeet Dhiman, Dr. Ritu Das THSTI, AIIMS, Aptabharat Innovation Private Limited Indian, Provisional NA
22 201811032275 A pharmaceutical composition for the treatment of TH17 cells mediated autoimmune diseases and uses thereof. Dr. Amit Awasthi, Dr. Amit Kumar Pandey, Dr. Shailendra Asthana, Zaigham Abbas Rizvi, Charu suri, Srikant Sadhu THSTI Indian, Provisional Open
23 201811022084 A pharmaceutical composition for the treatment of IL9 mediated autoimmune inflammatory diseases and uses thereof Amit Awasthi, Suyasha Roy THSTI Provisional Patent application Filed Open
24 201811023360 Aptamer against M.tb MPT51 and uses thereof. Dr. Jaya S. Tyagi, Dr. Tarun Kumar Sharma, Dr. Abhijeet Dhiman, Dr. Ritu Das THSTI | AIIMS | M/S Aptabharat Innovation Pvt. Ltd. Provisional Patent Application NA
25 201711036319 Chemical processes utilizing carbondioxide as a source of carbon Dinesh Mahajan, Varun Kumar, Anil Rana THSTI Provisional patent application Open
26 201811004996 A cyclic peptide and pharmaceutical composition coprising the same for the inhibition of HEV proliferation Dr. Milan Surjit, Saumya Anang THSTI Provisional patent application
27 201711046980 A rapid method of morphology-based antimicrobial drug susceptibility testing in biological fluids Dr. Niraj Kumar, Dr. Susmita Chaudhuri, Dr. Sagarika Haldar, Dr. Chandresh Sharma, Mr. Shrikant, Mr. Deepak Rathore, Mr. Subhash Chandra Tanwar, and Dr. Shinjini Bhatnagar THSTI Indian provisional Open
28 201711019482 A novel nucleophilic acyl substitution method of carboxylic acid and its anhydride derivatives catalyzed by novel reagents Dr. Dinesh Mahajan, Varun Kumar, Anil Rana, Chuttan Lal Meena, Nidhi Sharma, Anamika Thakur, Lata Tiwari THSTI Indian Provisional Open
29 PCT/IN2017/050369 Method of hyperplexing in mass spectrometry to elucidate temporal dynamics of proteome Dr. Kanury Subba Rao, Dr. Amit Kumar Yadav, Dr. Shilpa Jamwal, Dr. Suruchi Aggarwal, Dr. Ajay Kumar THSTI PCT application claiming priority of Indian application 201611029904 Open
30 201711031441 Novel compounds for liver disorders Dr. Kanury Rao, Dr. Dinesh Mahajan, Dr. S. Asthana, Dr. Shilpa Jamwal, Dr. Sameena Khan THSTI Indian Provisional Open
31 1133/DEL/2011 A method and device for detection of anti-transglutaminase antibodies Prof. Shinjini Bhatnagar, Dr. Uma Mouli Natchu, Dr. Nitya Wadhwa, Dr. Navin Khanna, Siddarth Datta Gupta, Savita Saini, Meena Pal, Poornima Tyagi THSTI, ICGEB, AIIMS FER received Licensed
32 62/189,418 HIV-1 Clade Envelope Glycoproteins Dr. Bimal Chakrabarty, Dr. Rajesh Kumar, Dr. Supratik Deshpandey, Dr. Shilpa Patil, Dr. Jayanta Bhattacharya THSTI, IAVI NA NA
33 62/254,971 HIV-1 Clade Envelope Glycoproteins Dr. Bimal Chakrabarty, Dr. Rajesh Kumar, Dr. Supratik Deshpandey, Dr. Shilpa Patil, Dr. Jayanta Bhattacharya THSTI, IAVI NA NA
34 WO2017007646 HIV-1 Clade Envelope Glycoproteins Dr. Bimal Ckakrabarty, Dr. Rajesh Kumar, Dr. Supratik Deshpandey, Dr. Shilpa Patil, Dr. Jayanta Bhattacharya THSTI, IAVI Published PCT application NA
35 201711016548 Engineered recombinant protein antigen of trimeric mimic of HIV-1 envelope glycoprotein spike Dr. Jayanta Bhattacharya, Dr. Rajesh Kumar, Dr. Shilpa Patil, Dr. Vivek Kumar THSTI Provisional Indian patent application NA
36 62/407,729 Stabilized Indian Clade C ENV Shubbir Ahmed, Tripti Shrivastava, Bimal k Chakrabarti THSTI, IAVI NA NA
37 62/407,734 Cleaved trimeric HIV Clade B ENV Supratik Das, Bimal K Chakrabarti THSTI, IAVI NA NA
38 62/334636 Engineered recombinant protein antigen of trimeric mimic of HIV-1 envelope glycoprotein spike Dr. Jayanta Bhattacharya, Dr. Rajesh Kumar, Vivek Kumar Yadav, Dr. Shilpa Patil THSTI, IAVI NA NA
39 201711001246 Novel DNA aptamers against nucleoid-associated protein HupB of Mycobacterium tuberculosis and uses thereof Dr. Tarun Kumar Sharma, Dr. Jaya Tyagi, Dr. Hanumanthappa Hari Krishna, Priya Kalra THSTI, AIIMS Indian Complete 28/09/2017 Open
40 10-1757629 5-nitro-1,10-phenanthloline derivatives and pharmaceutical composition for prevention and treatment of tuberculosis containing the same Lee Iii Young, Park Chan Yong, Jung Myoung Geun, Kaung Hyun Hye, Dr. Ramandeep Singh, Dr. Saqib Kidwai THSTI, KRICT Korea Granted (Republic of Korea) NA
41 78/DEL/2015 Drug Targeting Dr. Rajat Anand, Srikanth Ravichandran, Dr. Samrat Chatterjee THSTI Abandoned NA
42 201711009179 Novel molecules and their HIV inhibitory activity Dr. Kanury Rao, Dr. Dinesh Mahajan, Dr. S. Asthana, Dr. Shilpa Jamwal, Dr. Sameena Khan and D. Mitra THSTI Indian Provisional Open
43 201711009180 Novel molecules and their HIV inhibitory activity Dr. Kanury Rao, Dr. Dinesh Mahajan, Dr. S. Asthana, Dr. Shilpa Jamwal, Dr. Sameena Khan and D. Mitra THSTI Indian Provisional Open
44 2016152499 Novel Compounds as anti-Tubercular Agents Varshenya Singh , Dr. KV Subba Rao , Dr. Dinesh Mahajan, Sundeep Duggar THSTI, Sphaera Pharma Pvt. Ltd. Russian national phase patent application NA
45 2016/08676 Novel Compounds as anti-Tubercular Agents Varshenya Singh , Dr. KV Subba Rao , Dr. Dinesh Mahajan, Sundeep Duggar THSTI, Sphaera Pharma Pvt. Ltd. South Africa national phase patent application NA
46 EP3148518 Novel Compounds as anti-Tubercular Agents Varshenya Singh , Dr. KV Subba Rao , Dr. Dinesh Mahajan, Sundeep Duggar THSTI, Sphaera Pharma Pvt. Ltd. European national phase patent application NA
47 15/313986 Novel Compounds as anti-Tubercular Agents Varshenya Singh , Dr. KV Subba Rao , Dr. Dinesh Mahajan, Sundeep Duggar THSTI, Sphaera Pharma Pvt. Ltd. US national phase patent application NA
48 11-2016-0280814 Novel Compounds as anti-Tubercular Agents Varshenya Singh , Dr. KV Subba Rao, Dr. Dinesh Mahajan, Sundeep Duggar THSTI, Sphaera Pharma Pvt. Ltd. Brazil national phase patent application NA
49 2015800412540 Novel Compounds as anti-Tubercular Agents Varshenya Singh , Dr. KV Subba Rao, Dr. Dinesh Mahajan, Sundeep Duggar THSTI, Sphaera Pharma Pvt. Ltd. China national phase patent application NA
50 WO2015181837 Novel Compounds as anti-Tubercular Agents Varshenya Singh , Dr. KV Subba Rao , Dr. Dinesh Mahajan, Sundeep Duggar THSTI, Sphaera Pharma Pvt. Ltd. In PCT national phase NA
51 1431/DEL/2014 Novel Compounds as anti-Tubercular Agents Varshenya Singh , Dr. KV Subba Rao, Dr. Dinesh Mahajan, Sundeep Duggar THSTI, Sphaera Pharma Pvt. Ltd. In PCT National Phase NA
52 1055/DEL/2014 Novel Autophagy-inducing Compounds NA THSTI NA NA
53 1056/DEL/2014 Compounds for Induction of Autophagy NA THSTI NA NA
54 WO2016065252 Native Trimeric ENV Immunogen Design Dr. Bimal K Chakrabarti Dr. Saikat Boliar, Dr. Supratik Das, Dr. Tripti Shrivastava, King Charles Richter, Dr. Jayanta Bhattacharya, Dr. Sweety Samal THSTI, IAVI NA NA
55 62/068,202 Native Trimeric ENV Immunogen Design Dr. Bimal K Chakrabarti Dr. Saikat Boliar, Dr. Supratik Das, Dr. Tripti Shrivastava, King Charles Richter, Dr. Jayanta Bhattacharya, Dr. Sweety Samal THSTI, IAVI NA NA
56 62/155,673 Native Trimeric ENV Immunogen Design Dr. Bimal K Chakrabarti Dr. Saikat Boliar, Dr. Supratik Das, Dr. Tripti Shrivastava, King Charles Richter, Dr. Jayanta Bhattacharya, Dr. Sweety Samal THSTI, IAVI NA
57 201611029904 Method of hyperplexing in mass spectrometry to elucidate temporal dynamics of proteome Dr. Kanury Rao, Dr. Amit Kumar Yadav, Dr. Shilpa Jamwal, Suruchi Aggarwal, Dr. Ajay Kumar THSTI Indian Provisional Open
58 201611031991 Mammalian cell lines for enhanced production of Japanese encephalitis virus, the method to produce and uses thereof Dr. Sudhanshu Vrati, Dr. Manjula Kalia, Dr. Manish Sharma THSTI Indian Provisional NA
59 201611001550 Novel DNA aptamers against heat shock protein HspX of Mycobacterium tuberculosis and uses thereof Dr. Jaya Tyagi, Dr. Tarun Kumar Sharma, Dr. Abhijeet Dhiman THSTI | AIIMS Indian Complete Licensed
60 683/DEL/2015 Monoclonal Antibodies specific to Salmonella typhi flagellin, and use thereof. Dr. Ashutosh Tiwari, Dr. Anurag Sankhyan, Dr. Navin Khanna, Tarang Sharma, Dr. Chandresh Sharma, Prof. Shinjini Bhatnagar THSTI Indian Complete Licensed
61 1350/DEL/2015 Production of recombinant Cytolethal Distending Toxin B protein and its uses as diagnostic tool thereof Dr. Ashutosh Tiwari, Dr. Anurag Sankhyan, Dr. Navin Khanna, Tarang Sharma, Dr. Chandresh Sharma, Prof. Shinjini Bhatnagar THSTI Indian Complete Licensed
62 2291/DEL/2015 Human monoclonal antibodies specific to preS1 domain of Hepatitis B virus, and use thereof Dr. Ashutosh Tiwari, Dr. Anurag Sankhyan, Dr. Subrata Sinha, Dr. Navin Khanna, Dr. Subrat Acharya THSTI Indian Complete 25/08/2016 Open
63 2290/DEL/2015 Method of improving stability of recombinant protein product in CHO batch culture and uses thereof Dr. Susmita Chaudhuri, Dr. Niraj Kumar, Dr. Ashutosh Tiwari THSTI Indian Complete 25/08/2016 Open
64 2706/DEL/2015 A process for preparation of nanoparticles encapsulated antibacterial drug and the product obtained Dr. Amit Awasthi, Sakhshi Malik, Dr. Ramendra Pati Pandey THSTI Indian Complete 25/08/2016 Open
65 201611004727 Isolated nucleotide sequences useful for the prevention of HIV-1 infection Dr.Jayanta Bhattacharya, Dr. Suprit Deshpande, Dr. Shilpa Patil, Dr. Rajesh Kumar, Dr. Murugavel Kailapuri Gangatharan (YRG CENTRE FOR AIDS RESEARCH & EDUCATION) THSTI Indian Complete 26/08/2016 Open
66 201611021901 Aptamer against mycobacterial malate synthase and uses thereof Dr. Jaya S. Tyagi, Dr. Tarun Kumar Sharma, Dr. Abhijeet Dhiman, Ishara Datta, Chanchal Kumar THSTI | AIIMS Indian Complete 26/08/2016 Licensed

*After the last date the response to each technology will be reviewed on a quarterly basis.

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