Dr Wadhwa trained as a pediatrician and after practicing for a few years, transitioned to become a physician-scientist. She has been doing clinical research for more than a decade and leads her research programme at THSTI. In her initial years as a researcher at AIIMS-New Delhi, she was involved with the conduct of hypothesis driven studies that evaluated interventions directed at several commonly occurring infections in children in India. She was groomed in the skills required for conducting rigorous and meaningful research. In 2010, she joined Translational Health Science and Technology Institute as a physician-scientist. She has been associated with several large multi-centre clinical trials using zinc for treatment of various childhood illnesses, surveillance for H-influenzae B in tertiary hospitals, establishing a large cohort of pregnant women to find solutions for adverse pregnancy outcomes, and observational studies to understand the development and maturation of the neonatal immune system. Her primary research interest is finding solutions for neonatal and early life morbidity and mortality. She is the PI for a large multi-country multi-centre clinical trial to measure the efficacy of adjunct zinc for the treatment of young infant sepsis and co-PI on another large multi-country multi-site clinical trial to test the efficacy of immediate continuous KMC in reducing neonatal mortality.
She has been instrumental in establishing a large longitudinal cohort of pregnant women with the primary aim of building risk stratification algorithms for adverse outcomes and is overseeing the conduct including all aspects of data management of the cohort. She has demonstrated ability to establish, maintain and follow population and hospital cohorts with high quality data. Her core expertise lies in design, conduct and analysis of hypothesis driven multicentre hospital based clinical studies. She has built and lead multisite, multidisciplinary research teams that are capable of performing research to the most exacting standards of good clinical and ethical practices and to use risk and decision science for clinical medicine and public health.
She has authored many publications including one in Lancet and has co-authored chapters in text books. She has been credited with the development of revised Consensus guidelines for the management and treatment of diarrhoea in children for NRHM (2006 & 2007) as member of National Indian Academy of Paediatrics (IAP) and Management of Severe Acute Malnutrition (2006).
Clinical Development Services Agency (CDSA): Since 2017, she has been associated with CDSA as its faculty in-charge. She has extended her scientific training and analytical thinking to grow CDSA and establish it as an academic clinical research unit where the focus is on academia-led, multi-centre, clinical trials/studieson public health issues of national importance.
Data Management Centre (DMC):Instrumental in establishing the data management centre (DMC) at the Pediatric Biology Centre (PBC) and later of the translational research program at THSTI. Lead the data management for all clinical studies being conducted and coordinated by PBC.
She supported the organization in establishing the Institutional Ethics Committee for Human Research and in the registration of the IEC with CDSCO. Was a member secretary for the THSTI IEC for the first few years.
Teaching:Leads ‘Quantitative Methods in Research’ and ‘Clinical Trials’ modules, for PhD taught course at THSTI since 2016. Faculty for workshops on ‘Clinical Research Methodology’, ‘Good Clinical Practices’, Ethics in Biomedical Research’
#Corresponding author
1. Rees CA, Hooli S, King C, McCollum ED, Colbourn T, Lufesi N, Mwansambo C, Lazzerini M, Madhi SA, Cutland C, Nunes M, Gessner BD, Basnet S, Kartasasmita CB, Mathew JL, Zaman SMAU, Paranhos-Baccala G, Bhatnagar S, Wadhwa N, et al., World Health Organization PREPARE study group48. External validation of the RISC, RISC-Malawi, and PERCH clinical prediction rules to identify risk of death in children hospitalized with pneumonia. J Glob Health. 2021 Oct 9;11:04062. doi: 10.7189/jogh.11.04062. eCollection 2021. (I.F: 4.413)
2. WHO Immediate KMC Study Group* S. Arya, H. Naburi, K. Kawaza, S. Newton, C.H. Anyabolu, Wadhwa N, et al,. Immediate “Kangaroo Mother Care” and Survival of Infants with Low Birth Weight.N Engl J Med 2021; 384:2028-2038. doi: 10.1056/NEJMoa2026486. (I.F: 70.669)
3. Kumar S, Kumari N, Talukdar D, Kothidar A, Sarkar M, Mehta O, Kshetrapal P, Wadhwa N, Thiruvengadam T, Desiraju BP, Nair GB , Bhatnagar S, Mukherjee S, Das B, GARBH-Ini Study Group. The Vaginal Microbial Signatures of Preterm Birth Delivery in Indian Women. Front Cell Infect Microbiol 2021 May 13;11:622474. doi: 10.3389/fcimb.2021.622474. eCollection 2021. (I.F: 4.300)
4. Vijayram R, Damaraju N, Xavier A, Desiraju BK, Thiruvengadam R, Misra S, Chopra S, Khurana A, Wadhwa N, GARBH-Ini Study Group, Rengaswamy R, Sinha H, Bhatnagar S. Comparison of first trimester dating methods for gestational age estimation and their implication on preterm birth classification in a North Indian cohort. BMC Pregnancy Childbirth 2021 Apr 30;21(1):343. doi: 10.1186/s12884-021-03807-4.(I.F: 2.587)
5. Das J, Bagchi I, Ghosh S, Wadhwa N, Nachu UC, Thiruvengadam R, Kshetrapal P, Bhatnagar S, Majumder PP, Maitra A, GARBH-Ini Team. Pattern of variation in DNA methylation during pregnancy among mothers who delivered preterm in the GARBH-Ini cohort. Preprint from medRxiv, 2021;10 Sep 2021. doi: 10.1101/2021.09.02.21262698
6. Chaudhuri S, Thiruvengadam R, Chattopadhyay S, Mehdi F, Pallavi Kshetrapal, Shrivastava T, Desiraju BK, Batra G, Kang G, Bhatnagar S, DBT India Consortium for COVID-19 Research. Comparative evaluation of SARS-CoV-2 IgG assays in India. Comparative Study. J Clin Virol 2020 Oct;131:104609. doi: 10.1016/j.jcv.2020.104609. (Cited: 10, I.F: 2.049)
7. Thiruvengadam R, Chattopadhyay S, Mehdi F, Desiraju BK, Chaudhuri S, Singh S, Bhartia V, Kshetrapal P, Mouli Natchu UC, Wadhwa N, Sopory S, Wahi M, Pandey AK, Taneja J, Anand N, Sharma N, Sharma P, Saxena S, Sindhu D, Sindhu B, Sharma D, Shrivastava T, Dang A, Batra G, Kang G, Bhatnagar S; DBT India Consortium for COVID 19 Research. Longitudinal Serology of SARS-CoV-2-Infected Individuals in India: A Prospective Cohort Study. Am J Trop Med Hyg 2021 May 18:tpmd210164. doi: 10.4269/ajtmh.21-0164. Online ahead of print. (Cited: 01, I.F: 2.453)
8. Mehdi F, Chattopadhyay S, Thiruvengadam R, Yadav S, Kumar M, Sinha SK, Goswami S, Kshetrapal P, Wadhwa N, Chandramouli Natchu U, Sopory S, Koundinya Desiraju B, Pandey AK, Das A, Verma N, Sharma N, Sharma P, Bhartia V, Gosain M, Lodha R, Lamminmäki U, Shrivastava T, Bhatnagar S, Batra G. Development of a Fast SARS-CoV-2 IgG ELISA, Based on Receptor-Binding Domain, and Its Comparative Evaluation Using Temporally Segregated Samples From RT-PCR Positive Individuals. Front Microbiol 2021 Jan 20;11:618097. doi: 10.3389/fmicb.2020.618097. eCollection 2020. (Cited: 02, I.F: 4.076)
9. Kumar B, Dey AK, Saha S, Singh AK, Kshetrapal P, Wadhwa N, Thiruvengadam R, Desiraju BK, Bhatnagar S, Salunke DM, Rashid F, Malakar D, Maiti TK; GARBH-Ini Study Group. Dynamic Alteration in the Vaginal Secretory Proteome across the Early and Mid-Trimesters of Pregnancy. J Proteome Res. 2021 Feb 5;20(2):1190-1205. doi: 10.1021/acs.jproteome.0c00433. Epub 2021 Jan 26.(Cited: 01, I.F: 4.074)
10. WHO Immediate KMC Study Group*.Impact of continuous Kangaroo Mother Care initiated immediately after birth (iKMC) on survival of newborns with birth weight between 1.0 to < 1.8 kg: study protocol for a randomized controlled trial. Trials 2020 Mar 19;21(1):280. doi: 10.1186/s13063-020-4101-1. (Cited: 14, I.F: 1.883)
* Group Authorship
11. Mehta O, Ghosh TS, Kothidar A, Gowtham MR, Mitra R, Kshetrapal P, Wadhwa N, Thiruvengadam R; GARBH-Ini study group, Nair GB, Bhatnagar S, Das B. 2020. Vaginal Microbiome of Pregnant Indian Women: Insights into the Genome of Dominant Lactobacillus Species. Microb Ecol. Mar 23. doi: 10.1007/s00248-020-01501-0. [Epub ahead of print] (Cited: 06, I.F: 3.611)
12. Mani S, Shrivastava T, Bhattacharyya S, Rameshwaram N, Samal S, Goswami S, Kumar A, Singh R, Kumar N, Wadhwa N, Natchu UC, Thiruvengadam R, Sopory S, Kshetrapal P, Desiraju B, Bhartia V. A Luminex based serological assay for detecting IgM and IgG antibody response in SARS-CoV2 patients. Authorea. June 23, 2020. DOI: 10.22541/au.159294169.97530983
13. Dey AK, Kumar B, Singh AK, Ranjan P, Thiruvengadam R, Desiraju BK, Kshetrapal P, Wadhwa N, Bhatnagar S*, Rashid F, Malakar D, Salunke DM, Maiti TK; GARBH-Ini Study Group*. 2020. Salivary proteome signatures in the early and middle stages of human pregnancy with term birth outcome. Sci Rep. 10, 8022. https://doi.org/10.1038/s41598-020-64483-6 (Cited: 03, I.F: 4.525)
14. Agarwal A, Mukherjee A, Kumar G, Chatterjee P, Bhatnagar T, Malhotra P; PLACID Trial Collaborators. Convalescent plasma in the management of moderate covid-19 in adults in India: open label phase II multicentre randomised controlled trial (PLACID Trial). BMJ. 2020 Oct 22;371:m3939. doi: 10.1136/bmj.m3939. (Cited: 436, I.F: 39.89)
*PLACID Trial Collaborators: Anup Agarwal, Aparna Mukherjee, Gunjan Kumar, Pranab Chatterjee, Tarun Bhatnagar, Pankaj Malhotra, B Latha, Sunita Bundas, Vivek Kumar, Ravi Dosi, Janak Kumar Khambholja, Rosemarie de Souza, Raja Rao Mesipogu, Saurabh Srivastava, Simmi Dube, Kiran Chaudhary, S Subash, S Anbuselvi, V Rajendran, A Sundararajaperumal, P Balamanikandan, Leena Nakate, Samir Joshi, Rajesh Karyakarte, Suraj Goyanka, Nimisha Sharma, Nikhil Verma, Asim Das, Monika Bahl, Nitya Wadhwa, et al.
15. Bhatnagar S, Majumder PP, Salunke DM, Interdisciplinary Group for Advanced Research on Birth Outcomes—DBT India Initiative (GARBH-Ini)*. “A Pregnancy Cohort to Study Multidimensional Correlates of Preterm Birth in India: Study Design, Implementation, and Baseline Characteristics of the Participants.” Am J Epidemiol Apr 1;188(4):621-631.(Cited: 11, I.F: 4.473)
*MEMBERS OF GARBH-Ini:Translational Health Science and Technology Institute, NCR Biotech Cluster, Faridabad, Delhi NCR, India (Shinjini Bhatnagar, Vineeta Bal, Bhabatosh Das, Pallavi S. Kshetrapal, Sumit Misra, Balakrish G. Nair, Uma Chandra Mouli Natchu, Satyajit Rath, Kanika Sachdeva, Shailaja Sopory, Amanpreet Singh, Dharmendra Sharma, Ramachandran Thiruvengadam, Nitya Wadhwa); National Institute of Biomedical Genomics, Kalyani, West Bengal, India (Arindam Maitra, Partha P. Majumder); Regional Centre for Biotechnology, NCR Biotech Cluster, Faridabad, Delhi NCR, India (Tushar K. Maiti, Dinakar M. Salunke)
16. Rathore DK, Holmes TH, Nadeau KC, Mittal P, Batra A, Rosenberg-Hasson Y, Sopory S, Gupta R, Chellani HK, Aggarwal KC, Bal V, Natchu UCM, Bhatnagar S, Tavassoli M, Lyell DJ, Rath S, Wadhwa N#, Maecker HT#. Differences in multiple immune parameters between Indian and U.S. infants.PLoS One 2018 Nov 16;13(11):e0207297. doi: 10.1371/journal.pone.0207297. eCollection 2018. (Cited: 07, I.F: 3.234)
17. Chawla AS, Kanodia P, Mukherjee A, Jain V, Kaur G, Coshic P, Chatterjee K, Wadhwa N, Natchu UCM, Sopory S, Bhatnagar S, Majumder PP, George A, Bal V, Rath S, Prabhu SB. Cell-intrinsic regulation of peripheral memory-phenotype T cell frequencies.PLoS One. 2018 Dec 17;13(12):e0200227. doi: 10.1371/journal.pone.0200227. eCollection 2018. (Cited: 01, I.F: 3.234)
18. Singh P, Arora A, Strand TA, Sommerfelt H, Lodha R, Kabra SK, Aneja S, Natchu UCM, Chandra J, Rath B, Sharma VK, Kumari M, Saini S, Bhatnagar S, Wadhwa N. Predictors of death in infants with probable serious bacterial infection.Pediatr Res. 2018 Apr;83(4):784-790. doi: 10.1038/pr.2017.299(Cited: 01, I.F: 3.123)
19. Khullar B, Balyan R, Oswal N, Jain N, Sharma A, Abdin MZ, Bagga A, Bhatnagar S, Wadhwa N, Natchu UCM, George A, Rath S, Bal V, Sopory S. Interaction of CD80 with Neph1: a potential mechanism of podocyte injury.Clin Exp Nephrol. 2018 Jun;22(3):508-516. doi: 10.1007/s10157-017-1489-3. Epub 2017 Oct 11. (Cited: 16, I.F: 1.764)
20. Bagri NK, Bagri N, Jana M, Gupta AK, Wadhwa N, Lodha R, Kabra SK, Chandran A, Aneja S, Chaturvedi MK, Sodhi J, Fitzwater SP, Chandra J, Rath B, Kainth US, Saini S, Black RE, Santosham M, Bhatnagar S. Efficacy of Oral Zinc Supplementation in Radiologically Confirmed Pneumonia: Secondary Analysis of a Randomized Controlled Trial.J Trop Pediatr. 2018 Apr 1;64(2):110-117. doi: 10.1093/tropej/fmx036.(Cited: 05, I.F: 1.162)
21. Wadhwa N, Basnet S, Natchu UCM, Shrestha LP, Bhatnagar S, Sommerfelt H, Strand TA; zinc sepsis study group, Ramji S, Aggarwal KC, Chellani H, Govil A, Jajoo M, Mathur NB, Bhatt M, Mohta A, Ansari I, Basnet S, Chapagain RH, Shah GP, Shrestha BM. Zinc as an adjunct treatment for reducing case fatality due to clinical severe infection in young infants: study protocol for a randomized controlled trial. BMC Pharmacol Toxicol. 2017 Jul 10;18(1):56. doi: 10.1186/s40360-017-0162-5.(Cited: 02, I.F: 2.228)
22. Prabhu SB, Rathore DK, Nair D, Chaudhary A, Raza S, Kanodia P, Sopory S, George A, Rath S, Bal V, Tripathi R, Ramji S, Batra A, Aggarwal KC, Chellani HK, Arya S, Agrawal N, Mehta U, Natchu UC, Wadhwa N, Bhatnagar N. Comparison of Human Neonatal and Adult Blood Leukocyte Subset Composition Phenotypes.PLoS One. 2016 Sep 9;11(9):e0162242. doi: 10.1371/journal.pone.0162242. eCollection 2016. (I.F: 3.234).(Cited: 48, I.F: 3.234)
23. Bag S, Saha B, Mehta O, Anbumani D, Kumar N, Dayal M, Pant A, Kumar P, Saxena S, Allin KH, Hansen T, Arumugam M, Vestergaard H, Pedersen O, Pereira V, Abraham P, Tripathi R, Wadhwa N, Bhatnagar S, Prakash VG, Radha V, Anjana RM, Mohan V, Takeda K, Kurakawa T, Nair GB, Das B.. An Improved Method for High Quality Metagenomics DNA Extraction from Human and Environmental Samples. Sci Rep; 2016; 6:26775. doi: 10.1038/srep26775. (I.F: 5.578). (Cited: 111, I.F: 5.578)
24. Sodhi J, Satpathy S, Sharma DK, Lodha R, Kapil A, Wadhwa N, Gupta SK. Healthcare associated infections in Paediatric Intensive Care Unit of a tertiary care hospital in India: Hospital stay & extra costs.Indian J Med Res. 2016 Apr;143(4):502-6. (Cited: 16, I.F: 2.061)
25. Rathore DK, Nair D, Raza S, Saini S, Singh R, Kumar A, Tripathi R, Ramji S, Batra A, Aggarwal KC, Chellani HK, Arya S, Bhatla N, Paul VK, Aggarwal R, Agarwal N, Mehta U, Sopory S, Natchu UCM, Bhatnagar S, Bal V, Rath S, Wadhwa N. Underweight full-term Indian neonates show differences in umbilical cord blood leukocyte phenotype. PlosONE. 2015 Apr 21;10(4):e0123589. (Cited: 10, I.F.: 3.234)
26. Singh P#, Wadhwa N#, Lodha R, Sommerfelt H, Aneja S, Natchu UC, Kabra SK, Bhatnagar S#, Strand TA. Predictors of time till recovery in infants with probable serious bacterial infections. PlosONE. 2015 Apr 24;10(4):e0124594. (Cited: 02, I.F.: 3.234)
27. Singh P# and Wadhwa N#, Chaturvedi MK, Bhatia V, Saini S, Tandon N, Makharia GK, Maki M, Not T, Phillips A, Bhatnagar S. Validation of point-of-care testing for coeliac disease in children in a tertiary hospital in North India. Arch Dis Child. 2014;99(11):1004-8. (Cited: 26, I.F: 2.905)
28. Dwivedi S, Das BK, Aneja S, Sharma S, Chaturvedi MK, Kahn G, Fitzwater SP, Chandran A, Wadhwa N, Bhatnagar S.Group B Streptococcal Meningitis in Infants Beyond the Neonatal Period.Indian J Pediatr2014 Jan;81(1):4-8. (Cited: 07, I.F: 0.867)
29. Tandon M, Pandey VK, Dubey GK, Pandey CK, Wadhwa N. 2014. Addition of sub-anaesthetic dose of ketamine reduces gag reflex during propofol based sedation for upper gastrointestinal endoscopy: A prospective randomised double-blind study. doi: 10.4103/0019-5049.138981. Indian J Anaesth 2014 Jul;58(4):436-41.
30. Singh P, Wadhwa N, Chaturvedi MK, Bhatia V, Tandon N, Makharia GK, Mäki M, Not T, Phillips A, Bhatnagar S. Su1451 Validation of Point of Care Testing for Celiac Disease in Children in a Tertiary Hospital in North India. Gastroenterol 2014; 146, (5): Supp 1, S-472.
31. Wadhwa N, Chandran A, Aneja S, Lodha R, Kabra SK, Chaturvedi MK, Sodhi J, Fitzwater SP, Chandra J, Rath B, Kainth US, Saini S, Black RE, Santosham M, Bhatnagar S. Efficacy of zinc given as an adjunct in the treatment of severe and very severe pneumonia in hospitalized children 2-24 mo of age: a randomized, double-blind, placebo-controlled trial. Am J Clin Nutr 2013;97(6):1387-94. (Cited: 36, I.F: 6.8)
32. Ramachandran P, Fitzwater SP, Aneja S, Verghese VP, Kumar V, Nedunchelian K, Wadhwa N, Veeraraghavan B, Kumar R, Meeran M, Kapil A, Jasmine S, Kumar A, Suresh S, Bhatnagar S, Thomas K, Awasthi S, Santosham M, Chandran A. Prospective multi-centre sentinel surveillance for Haemophilus influenzae type b & other bacterial meningitis in Indian children. Indian J Med Res 2013; 137(4):712-20. (Cited: 26, I.F: 2.061)
33. Bhatnagar S, Natchu UCM, Wadhwa N, Lodha R, Sommerfelt H, Strand TA. Zinc for probable serious bacterial infection in infants–Authors' reply. Lancet. 2012; 380; (9848), P1144. doi.org/10.1016/S0140-6736(12)61660-2.
34. Bhatnagar S, Wadhwa N, Aneja S, Lodha R, Kabra SK, Natchu UC, Sommerfelt H, Dutta AK, Chandra J, Rath B, Sharma M, Sharma VK, Kumari M and Strand TA. Zinc as adjunct treatment in infants aged between 7 and 120 days with probable serious bacterial infection: a randomised, double-blind, placebo-controlled trial. Lancet. 2012;379(9831):2072-8. (Cited: 90, I.F: 45.217)
35. Wadhwa N,Natchu UCM, SommerfeltH, Strand TA, Kapoor V, Saini S, Kainth UPS, Bhatnagar S. Oral rehydration solution is a poor vehicle for zinc in the treatment of acute childhood diarrhea. J Pediatr Gastroenterol Nutr. 2011 Aug; 53(2):161-7. (Cited: 21, I.F: 2.625)
36. Bhatnagar S, Bhatia V, Wadhwa N, Kumar Harish. Low osmolarity ORS and Zinc supplementation in the management of acute watery diarrhea: Current Management Practices. Ind J Pediatr 2008; 75(SS1) S53-6. (I.F: 0.867)
37. Bhatnagar S, Wadhwa N, Bhatia V, Aggarwala A. Practical issues in dietary management of persistent diarrhea in developing countries. Ind J Pediatr 2008;75(SS1)S123-8. (I.F: 0.867)
38. Bhatnagar S, Lodha R, Choudhury P, Sachdev HP, Shah N, Narayan S, Wadhwa N, Makhija P, Kunnekel K, Ugra D. Consensus statement of the IAP National Task Force: status report on management of acute diarrhea. Indian Pediatr 2007;44:380-9. (Cited: 75, I.F.: 1.036)
39. Bhatnagar S, Lodha R, Choudhury P, Sachdev HP, Shah N, Narayan S, Wadhwa N, Makhija P, Kunnekel K, Ugra D. IAP guidelines 2006 on hospital based management of severely malnourished children (adapted from the WHO Guidelines). Indian Pediatr 2007;44:443-61.(Cited: 27, I.F: 1.036)
40. Bhatnagar S, Tandon N. Diagnosis of Celiac Disease. Indian J Pediatr 2006;73(8):703-9. (Cited: 39, I.F.: 0.867)
In Journals of National Societies/Professional Associations, not included in medical database:
Bhatnagar S, Bhatia V, Wadhwa N. Probiotics and their use in childhood diarrhea. Proceedings of the ICMR Second Probiotic Symposium, Pub: Oxford & IBH 2008;71-82.
Authorship / Editorship of Monographs:
Bhatnagar S, Kumar H, Anand VK, Wadhwa N. Advisor Bhan MK. Revised guidelines for management of diarrhea in children for medical officers and health workers. Ministry of Health, August, 2007.
Chapters in text books
- Bhatnagar S, Lodha R, Bhatia V, Wadhwa N, Agarwala A. Nutrition. Ghai Essential Pediatrics, 7th Edn. Pub: CBS & Distributors 2009;57-77.
II. Details of technology transferred/ developed and patent filled:
1. Bhatnagar S, Khanna N, Natchu UC, Wadhwa N, Gupta S, Bagga A, Saini S. “A method and device for detection of anti-transglutaminase antibodies” (patent no. 1133/DEL/2011 dated 18-04-2011).
Collaborated with International Center of Genetic Engineering and Biology, AIIMS and to develop easily available indigenous, rapid, sensitive and specific diagnostic tests for Celiac Disease.
Transferred the technology to JMitra in 2013 as per DBT guidelines
The ELISA and the rapid point of care tests were commercialized by the industry in October 2014 (Patent NO 1133/DEL/2011; dated 18.04.2011). JMitra & Co (industrial partner)
I. As Principal Investigator/ Co-PI:
Inter-Institutional Program for Maternal, Neonatal and Infant Sciences-A translational approach-interdisciplinary Group for Advanced Research on BirtH outcomes-DBT INdia Initiative (GARBH-Ini Phase II)
Funding Agency: Department of Biotechnology, Government of India
Role in project: Co-Principal Investigator
Study period: 2021-2025
Equity and financial household impact in randomised controlled trials, implementation research and cohort studies in India (EQUIFINANCE)
Funding Agency: The Research Council of Norway
Role in project: Co-Principal Investigator
Study period: 2021-2025
ORCHESTRA: Connecting European Cohorts to Increase Common and Effective Response to SARS-CoV-2 Pandemic
Funding Agency: Department of Biotechnology, Government of India
Role in project: Co-Principal Investigator
Study period: 2020-2022
South Asian Breast Cancer Risk Prediction, Genetic Testing and Health Management (SURAKSHA): seed funding
Funding Agency: Affordable Approaches to Cancer Initiative, CRUK and Department of Biotechnology, Govt of India
Role in project: Co-Principal Investigator
Study period: 2020
Multiomics for Mothers and Infants (MOMI)
Funding Agency: Bill and Melinda Gates Foundation, USA via Grand Challenges India, BIRAC
Role in project: Principal Investigator along with 3 other PIs
Study period: 2020-2022
Zinc as adjunct for treatment of clinical severe infection in infants younger than 2 months: health gain, financial risk protection and cost-effectiveness analysis
Funding Agency: Centre for Intervention Science in Maternal & Child Health, Norway
Role in project: Principal Investigator
Study period: 2019-2022
The follow-up study to evaluate the impact of continuous KMC initiated immediately after birth compared to KMC initiated after stabilization in newborns with birth weight 1.0 to <1.8 kg on their neurodevelopmental outcomes in low-resource settings
Funding Agency: Bill and Melinda Gates Foundation, USA
Sponsor: World Health Organisation, Geneva
Role in project: Co-PI for India site
Study period: 2019-2022
Digoxininpatientswithrheumaticheartdisease: arandomisedplacebo-controlledtrial
Funding Agency: Indian Council of Medical Research
Role in project: Co-Principal Investigator
Study period: 2020-2024
Translational Research Consortium for Establishing Platform Technologies to Support Prophylactic and Therapeutic Strategies for Dengue Discovery to Proof-of-Concept
Funding Agency: National Biopharma Mission (NBM), Biotechnology Industry Research Assistance Council (BIRAC)
Role in project: Co-Principal Investigator
Study period: 2019-2022
“Bench to bedside” model for clinical and translational science between academic research institutes and hospitals focused on fetal growth restriction and preterm birth
Funding Agency: Department of Biotechnology, Government of India
Role in project: Co-Principal Investigator
Study period: 2018-2021
A multi-country randomized clinical trial to evaluate the impact of continuous KMC initiated immediately after birth compared to KMC initiated after stabilization in newborns with birth weight 1.0 to <1.8 kg on their survival in low-resource settings
Funding Agency: Bill and Melinda Gates Foundation, USA
Sponsor: World Health Organisation, Geneva
Role in project: Co-Principal Investigator for India site
Study period: 2017-2020
Stress outcomes on pregnancy, fetal growth and birth weight: Development of methods to identify mothers at risk of preterm birth and intrauterine growth restriction resulting from maternal stress
Funding Agency: BIRAC under Grand Challenges India - ‘All Children Thriving’ Initiative
Role in project: Co-Principal Investigator
Study period: 2017-2019 (Project completed)
Understanding the distinct development and functional properties of the neonatal immune system and their clinical consequences in the neonatal period
Funding Agency: Department of Biotechnology, Government of India
Role in project: Co-Principal Investigator
Study period: 2015-2019 (Project completed)
Zinc as an adjunct for the treatment of very severe disease in infants younger than 2 months
Funding Agency: Research Council of Norway; and
Centre for Intervention Science in Maternal & Child Health, Norway
Role in project: Coordinating Principal Investigator
Study period: 2015-2022
Inter-Institutional Program for Maternal, Neonatal and Infant Sciences-A translational approach to studying Preterm birth
Funding Agency: Department of Biotechnology, Government of India
Role in project: Co-Principal Investigator
Study period: 2013-2021
Comparison of immune markers of healthy adults with term neonates
Funding Agency: PBC Core Funds, THSTI
Role in project: Principal Investigator
Study period: 2012-2014 (Project completed)
Cross sectional study of cord blood immune markers in term appropriate for gestational age and small for gestational age neonates
Funding Agency: PBC Core Funds, THSTI
Role in project: Principal Investigator
Study period: 2011-2013 (Project completed)
II. As Co-Investigator:
Severe SARS-CoV2 related disease in low-and-middle-income country children aged 0-19 years: a multi-country observational study in a network of hospitals
Funding Agency: World Health Organisation
Role in project: Co- Investigator
Study period: 2021
Covid-19 Bioresource at the NCR Biotech Science Cluster
Funding Agency: Department of Biotechnology, Government of India
Role in project: Co- Investigator
Study period: 2021-2023
Abbreviated immune checkpoint inhibition following radical treatment across the mucosal squamous cell cancers (IMPART): seed funding
Funding Agency: Affordable Approaches to Cancer Initiative, CRUK and Department of Biotechnology, Govt of India
Role in project: Co- Investigator
Study period: 2020
Creation of a bio-repository and imaging data bank for accelerating evidence generation to facilitate children to thrive
Funding Agency: BIRAC under Grand Challenges India - ‘All Children Thriving’ Initiative
Role in project: Co- Investigator
Study period: 2016-2019
Social Innovation Immersion Programme (SIIP)
Funding Agency: BIRAC
Role in project: Co- Investigator
Study period: 2014-2016 (Project completed)
Neonatal immune profiles: infections and toxicants
Funding Agency: Department of Biotechnology, Government of India
Role in project: Co-Investigator
Study period: 2014-2015 (Project completed)
Vitamin D supplementation to improve immune responses to vaccines administered in early infancy – The Nutrivac-D Trial
Funding Agency: Department of Biotechnology, Government of India
Role in project: Co-Investigator
Study period: 2011-2016 (Project completed)
Collaboration for translational and clinical research between Translational Health Science and Technology Institute, National Brain Research Centre, Regional Centre for Biotechnology and Gurgaon Civil HospitalFunding Agency: Department of Biotechnology, Government of India
Role in project: Co-Investigator
Study period: 2010-2015 (Project completed)
Development of a rapid diagnostic test for diagnosis of celiac disease
(Phase I-II)
Funding Agency: Department of Biotechnology, Government of India
Role in project: Co-Investigator
Study period: 2010-2014 (Project completed)
Hib Meningitis Sentinel Surveillance in North India
Funding Agency: Johns Hopkins Bloomberg School of Public Health, USA
Role in project: Co-Investigator
Study period: 2008-2014 (Project completed)
1. Ms Divya Pillai, PhD Student
2. Ms Taruna, PhD student
3. Dr Mudia Gosain, PhD student